Topic: Brigham And Women'S Hospital

Scientists find genes linked to migraines

Scientists have uncovered a trio of genes tied to migraine headaches, including one in which the link is exclusive to women, according to a study published Sunday.Migraines are acutely debilitating headaches -- sometimes with an "aura", in which patients have the impression ...

2009 Infection Prevention-Hospital Cleaning Survey

The important link between environmental cleanliness and infection prevention has long been appreciated, but how best to achieve these objectives remains a source of ever-changing science and application. Nearly one in four are augmenting observation-based audits and performance goals with newer technologies ...

A Decade Later, Genetic Map Yields Few New Cures

Ten years after President Bill Clinton announced that the first draft of the human genome was complete, medicine has yet to see any large part of the promised benefits. For biologists, the genome has yielded one insightful surprise after another. But the ...
Proper coordination of cholesterol biosynthesis and trafficking is essential to human health. 2 Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA. 3 Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Charlestown, MA 02129, USA. 5 Cardiovascular Research Center, ...
An oncogene tumor-suppressor cascade may drive metastatic prostate cancer, according to research published online Feb. 14 in Nature Medicine.. Junxia Min, Ph.D., of Brigham and Women's Hospital in Boston, and colleagues performed a protein and transcriptional pattern analysis in more than 250 ...

How clean is clean?

The important link between environmental cleanliness and infection prevention has long been appreciated, but how best to achieve these objectives remains a source of ever-changing science and application. Nearly one in four are augmenting observation-based audits and performance goals with newer technologies ...

Hospital to Collect Patients' Genomic Data

Boston's Brigham and Women's Hospital (BWH) has announced plans to collect blood samples for genetic analysis from all consenting patients and then feed that information into a large database, allowing scientists to analyze patients' genomes alongside detailed medical histories. Christine Seidman, director ...
Girls who begin menstruation earlier than average have a greater chance of being short and fat and are at greater risk for breast cancer and endometrial cancer later in life. Further research into these genes could improve understanding of all the related ...
The abundance of cellular proteins is determined largely by the rate of transcription and translation coupled with the stability of individual proteins. We present a highly parallel multiplexing strategy to monitor protein turnover on a global scale by coupling flow cytometry with ...
Ubiquitin-mediated proteolysis regulates all aspects of cellular function, and defects in this process are associated with human diseases. We established and applied genetic technologies that combine global protein stability (GPS) profiling and genetic perturbation of E3 activity to screen for substrates of ...
Previous
  • 1
  • 2